Ed is a friend to Edd and Eddy, and almost the opposite of both: strong, tall, and dumb. He wears a green jacket over top a red-and-white striped shirt and blue jean pants, and has a unibrow and what seems to be a buzz cut. He has a strong love for comic books, gravy, chickens, buttered toast, and B-movies, and during the series he oddly is shown to have almost super powers (Ed's Amazing Strength, strong enough to lift a house easily, extreme invulnerability to pain, and the ability to enter television shows), the only constant super powers in Ed, Edd n Eddy.
He also has a little kid sister, Sarah, who despised him and the other Eds alongside the other kids during the series (up until the series' finale).
In FusionFall, when the Fusion Invasion arrives on Earth, Ed, Edd, and Eddy are watching the sky when the first Terrafuser swoops past them. Ed suggests that it looks like a giant jawbreaker. He and Edd are curiously absent in the future world (along with the other Cul-de-Sac kids, who are strangely also absent in the past Cul-de-Sac). Eddy says to the player that "Big Ed isn't around anymore." Ed and Edd likely fell in the initial invasion of Fuse.
In the past, Ed can be found in Mt. Blackhead, having wound up there after escaping pursuit from May Kanker. Ed has seemingly proclaimed himself as "The King of the Jungle," going so far as to adopt a stereotypical "kingly" accent when he talks, calling the Hero a "servant." He tells the player to tell Double D that he likes it where he is and he wants to stay forever.
- Ed is the last Blastons Nano of the game.
- Ed and Eddy are the only characters of their show, apart from the Kankers, to have a sibling (Sara), but that sibling is not seen or mentioned in the game.
- Ed doesn't want to go back to the Cul-de-Sac because he thinks he's the King of the Jungle.
- Ed is the only member of the Eds to have only two Fusions for the player to fight. Edd and Eddy both have three.